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The Sen Gupta laboratory on Bio-inspired Engineering for Advanced Therapies (BEAT) was founded in 2007. To date, the laboratory has received funding from foundation grants, state grants and federal grant mechanisms.

  • CDMRP PRMRP IIRA Award (Sen Gupta, PI): SanguiStop: Intravenous Nanomedicine for Targeted Thrombin Delivery in Hemorrhage Control. 2022-2026.

  • NIH R01 (Sen Gupta, PI): Heteromultivalent Peptide-Lipid Nanoconstructs as Artificial Platelet Analogs. 2021-2025.

  • CDMRP PRMRP Tech Development Award (Sen Gupta, PI): Field-Deployable Dried Platelet Surrogate Nanotechnology for Hemorrhage Control in RDCR. 2020-2023.

  • NIH R01 (Sen Gupta, PI): Mechanisms of platelet exosome-mediated acute chest syndrome in sickle cell disease. 2019-2023.
  • Department of Defense DMRDP (Sen Gupta, PI): SynthoPlate: Nanotechnology for Intravenous Hemostasis and Wound Healing in Prolonged Field Care. 2017-2022.
  • Ohio Technology Validation and Start-up Fund (Sen Gupta, PI): SynthoPlate Nanotechnology: Optimization and Validation. 2016-2017.
  • Case Coulter Translational Research Partnership (CCTRP) grant (Sen Gupta, PI): SynthoPlate Nanotechnology Evaluation in Pig Model. 2016-2017.
  • NCAI-CCF (NIH Center for Accelerated Innovation-Cleveland Clinic) grant (Sen Gupta, PI): SynthoPlate Nanotechnology Evaluation in Pig Model. 2015-2016.
  • NIH R01  (Sen Gupta, PI): Platelet-inspired Delivery System for Targeted Thrombolytic Therapy. 2015-2020.
  • NIH R01  (Sen Gupta, PI): Heteromultivalent Peptide-Lipid Nanoconstructs as Artificial Platelet Analogs. 2014-2019.
  • Case Comprehensive Cancer Center ACS IRG pilot grant (Sen Gupta, PI): A platelet-insired Nanomedicine Platform for Metastasis-targeted Drug Delivery. 2013-2014.
  • VA Merit Award (Sen Gupta, Co-I): In vivo performance of a high efficiency microfabricated artificial lung. 2011-2015.
  • NIH SBIR Phase I (IASIS Molecular Devices, Sen Gupta Co-I): A Novel Electrospun Vascular Graft. 2010-2013.
  • NIH SBIR Phase I (Nanomimetics, Sen Gupta Co-I): Fluorosurfactant polymers for vascular interface applications. 2010-2011.
  • American Heart Association Beginning Grant-in-Aid (Sen Gupta, PI): Functionally Integrated Liposomes as Synthetic Platelet Substitutes. 2007-2010.
  • NIH SBIR Phase I (AEGIS Biosciences, Sen Gupta Co-I): Peptide-modified Sulfonated Styrene Block Copolymers for Vascular Applications. 2007-2009.
  • NIH SBIR Phase I (Nanomimetics, Sen Gupta Co-I): Platelet Liposomal Drug Delivery — Thrombosis/Restenosis. 2005-2008.
  • Ohio Board of Regents, Case Presidential Research Initiative (Sen Gupta, PI): Hemostatically Active Liposomes as Synthetic Platelet Substitutes. 2007-2009.