Dr. Sen Gupta and the BEAT laboratory has been awarded a new 5 year NIH R01 research grant ($1.9 million), an NCAI innovation grant ($250K) and a CCTRP translational research grant ($125K) to advance research in the area of platelet-inspired technologies, especially Synthetic Platelets and Thrombus-targeted Drug Delivery system. Previously in 2014, Dr. Sen Gupta had received another 5 year NIH R01 grant for his research on Synthetic Platelets. The two back-to-back R01 grants will help the laboratory to refine the platelet-inspired designs to develop Clot Makers and Clot Breakers by modulating the chemistry and composition of the synthetic particle platforms and payloads. The additional innovation and translational research grants will assist in advancing the evaluation of the technologies in large animal (pig) models of hemostasis and thrombosis. In these areas, the laboratory has established collaborations with Cleveland Clinic, University Hospitals and University of Pittsburgh Medical Center.
The CCTRP grant news was recently highlighted in Case Daily:
Ujjal Didar Singh Sekhon, PhD student, gave a podium presentation at Biomedical Engineering Society (BMES) Annual Conference 2015 in Tampa, Florida on research project titled ‘Prophylactic Delivery of Synthetic Platelets Enhances Hemostasis in Severely Thrombocytopenia Mice’. This research is in collaboration with Dr. Keith McCrae’s lab at the Cleveland Clinic. Ujjal gave an excellent talk and also received a $450 travel award from the BMES chapter at Case Western. Congratulations Ujjal!